The dataset contains a list of cardiac and vascular biomarkers that were obtained on each day a participant visited the EPA Human Studies Facility. It also contains ozone concentrations on those days, which are publicly available on the EPA AirNow website. This dataset is not publicly accessible because: The dataset pertains to human research. It can be accessed through the following means: Requests to access data should be sent to Robert Devlin at devlin.robert@epa.gov. Format: The metadata are in the form of spreadsheets with health endpoints listed in columns and each human participant listed as a row. Similar spreadsheets contain exposure information in columns and participants in rows. This dataset is associated with the following publication: Mirowsky, J., M. Carraway, R. Dhingra, H. Tong, L. Neas, D. Diaz-Sanchez, W. Cascio, M. Case, J. Crooks, E. Hauser, E. Dowdy, W. Krause, and R. Devlin. Ozone exposure is associated with acute changes in inflammation, fibrinolysis, and endothelial cell function in coronary artery disease patients. ENVIRONMENTAL HEALTH. Academic Press Incorporated, Orlando, FL, USA, 16: 126, (2017).
Cardiovascular Physiologic and Systemic Responses to Sequential Exposure to Nitrogen Dioxide and Ozone in Rats. This dataset is associated with the following publication: Farraj , A., F. Malik, N. Coates , L. Walsh , D. Winsett , D. Terrell , L. Thompson, W. Cascio , and M. Hazari. Morning NO2 Exposure Sensitizes Hypertensive Rats to the Cardiovascular Effects of Same Day O3 Exposure in the Afternoon. INHALATION TOXICOLOGY. Informa Healthcare USA, New York, NY, USA, 28(4): 170-179, (2016).