The Office of Manufacturing and Energy Supply Chains is responsible for strengthening and securing manufacturing and energy supply chains needed to modernize the nation’s energy infrastructure and support a clean and equitable energy transition. The office is catalyzing the development of an energy sector industrial base through targeted investments that establish and secure domestic clean energy supply chains and manufacturing, and by engaging with private-sector companies, other Federal agencies, and key stakeholders to collect, analyze, respond to, and share data about energy supply chains to inform future decision making and investment. The office manages programs that develop clean domestic manufacturing and workforce capabilities, with an emphasis on opportunities for small and medium enterprises and communities in energy transition. The Office of Manufacturing and Energy Supply Chains coordinates closely with the Office of Clean Energy Demonstrations for the management of major demonstration projects, and across all of DOE’s programs on manufacturing and supply chain issues, including with the Advanced Manufacturing Office in the Office of Energy Efficiency and Renewable Energy.