This dataset provides zooplankton density and biomass information for each station visited during the three past Lake Superior CSMI surveys summarized by major taxonomic groups. Also included is the design weights for the surveys, which allow you to do the various statistical tests that we did in the paper. This dataset is associated with the following publication: Pawlowski, M., and M. Sierszen. A lake-wide approach for large lake zooplankton monitoring: Results from the 2006–2016 Lake Superior Cooperative Science and Monitoring Initiative surveys. JOURNAL OF GREAT LAKES RESEARCH. International Association for Great Lakes Research, Ann Arbor, MI, USA, 46(4): 1015-1027, (2020).