The widespread use of copper-treated lumber has increased the potential for human exposure. Moreover, there is a lack of information on the fate and behavior of copper-treated wood particles following oral ingestion. In this study, the in vitro bioaccessibility of copper from copper-treated wood dust in simulated stomach fluid and DI water was determined. Three copper-treated wood products, liquid alkali copper quaternary and two micronized copper quarternary from different manufacturers, were incubated in the extraction media then fractionated by centrifugation and filtration through 0.45 m and 10 kDa filters. The copper concentrations from isolated fractions were measured using Inductively Coupled Plasma-Optical Emission Spectrometry (ICP-OES). Total amounts of copper from each wood product were also determined using microwave-assisted acid digestion of dried wood samples and quantification using ICP-OES. The percent in vitro bioaccessible copper was between 83 and 90 % for all treated wood types. However, the percent of copper released in DI water was between 14 and 25 % for all wood products. This data suggests that copper is highly bioaccessible at low pH and may pose a potential human exposure risk upon ingestion. This dataset is associated with the following publication: Santiago-Rodrigues, L., J.L. Griggs, K. Bradham , C. Nelson , T. Luxton , W. Platten , and K. Rogers. Assessment of the bioaccessibility of micronized copper wood in synthetic stomach fluid. Environmental Nanotechnology, Monitoring and Management. Elsevier B.V., Amsterdam, NETHERLANDS, 4: 85-92, (2015).
OwnerUnited State Environmental Protection Agency - view all
Update frequencyunknown
Last updatedabout 1 year ago
Format
Overviewbioaccessibilitycopperhuman exposuremicronized coppersynthetic stomach fluidwood
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KeyValue
dcat_modified2016-09-07
dcat_publisher_nameU.S. EPA Office of Research and Development (ORD)
guidA-tx9t-277
ib1_trust_framework[]
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