This is the dataset for the research article "A Risk-Based Evaluation of Onsite, Non-Potable Reuse Systems Developed in Compliance with Conventional Water Quality Measures". It compiles the risk results for various reuse configurations and treatment levels that are described in the text. This dataset is associated with the following publication: Schoen, M., M. Jahne, and J. Garland. A Risk-Based Evaluation of Onsite, Non-Potable Reuse Systems Developed in Compliance with Conventional Water Quality Measures. JOURNAL OF WATER AND HEALTH. IWA Publishing, London, UK, 18(3): 331-334, (2020).