Data for publication Turley et al. "Applying the RISK21 approach to assess predictivity of new approach methodologies in toxicity testing and exposure assessment: a case study on food contact chemicals". Includes food concentration predictions from the model of Biryol et al. (2017) and SHEDS-HT exposure predictions. This dataset is associated with the following publication: Turley, A., K. Isaacs, B. Wetmore, A. Karmaus, M. Embry, and M. Krishan. Incorporating new approach methodologies in toxicity testing and exposure assessment for tiered risk assessment using the RISK21 approach: Case studies on food contact chemicals. FOOD AND CHEMICAL TOXICOLOGY. Elsevier Science Ltd, New York, NY, USA, 134: 110819, (2019).