This Science Hub file provides access to raw data published in Environmental Health Perspectives from the publication entitled Stress Drivers of Glucose Dynamics during Ozone Exposure Measured Using Radiotelemetry in Rats. This study used implantable telemetry in rats to assess real-time changes in circulating glucose during and after exposure to ozone and mechanistically linked responses to neuroendocrine stress hormones. This dataset is associated with the following publication: Henriquez, A., S. Snow , T. Jackson, J. House, A. Motsinger-Reif, C. Ward-Caviness, M.C. Schladweiler, D. Aelwel, C. Miller, A. Farraj, M. Hazari, R. Grindstaff, D. Diaz-Sanchez, A. Ghio, and U. Kodavanti. Stress Drivers of Glucose Dynamics during Ozone Exposure Measured Using Radiotelemetry in Rats. ENVIRONMENTAL HEALTH PERSPECTIVES. National Institute of Environmental Health Sciences (NIEHS), Research Triangle Park, NC, USA, 130(2): 127006, (2022).