Data from manuscript entitled: "Implications for modeling anion exchange treatment of perfluoroalkyl substances in drinking water and related natural organic impacts: a pilot study". This dataset is associated with the following publication: Smith, S., D. Wahman, E. Kleiner, B. Gray, T. Sanan, E. Stebel, C. Gastaldo, E. Hughes, S. Pedigo, B. Datsov, M. Lathrop-Allen, I. Bass, J. Quinn, G. Abulikemu, J. Pressman, G. Sorial, and L. Haupert. Implications for modeling anion exchange treatment of perfluoroalkyl substances in drinking water and related natural organic impacts: a pilot study. WATER RESEARCH. Elsevier Science Ltd, New York, NY, USA, 288: 124685, (2026).