Supplementary Files 1-15 contain the generated assay data that was used to establish BMAD and determine treatment effects. The tabbed spreadsheet data is formatted so that it can be directly analyzed, once converted to individual comma-separated values (.csv) files, using the R code provided in Supplementary File 16. Column headings are described in the supplemental file 'Metadata Glossary.docx'. This dataset is associated with the following publication: Angrish, M., C. McQueen, E. Hubal, M. Bruno, Y. Ge, and B. Chorley. Mechanistic Toxicity Tests Based on an Adverse Outcome Pathway Network for Hepatic Steatosis. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 159(1): 159-169, (2017).