The dataset contains national trends for 432 species of moths (mostly macro-moths) estimated using the moth data collected by Rothamsted Insect Survey (RIS) from their national light-trap network between the years 1968 and 2016. The trends were calculated using a Generalised Abundance Index (GAI) model. The trends are presented as year coefficients from the statistical model, Annual Growth Rates (AGR), and the total percentage changes over the whole time series. For each trend metric 95% and 90% confidence intervals are also provided. The dataset additionally contains a related set of trends produced specifically for the Atlas of Britain & Ireland’s Larger Moths which used a restricted subset of the data from UK analysis, specifically only using data from traps in Great Britain and only data from 1970 and 2016.