Files included are original data inputs on stream fishes (fish_data_OEPA_2012.csv), water chemistry (OEPA_WATER_2012.csv), geographic data (NHD_Plus_StreamCat); modeling files for generating predictions from the original data, including the R code (MVP_R_Final.txt) and Stan code (MV_Probit_Stan_Final.txt); and the model output file containing predictions for all NHDPlus catchments in the East Fork Little Miami River watershed (MVP_EFLMR_cooc_Final). This dataset is associated with the following publication: Martin, R., E. Waits, and C. Nietch. Empirically-based modeling and mapping to consider the co-occurrence of ecological receptors and stressors. SCIENCE OF THE TOTAL ENVIRONMENT. Elsevier BV, AMSTERDAM, NETHERLANDS, 613(614): 1228-1239, (2018).