These data are extracted from output from the Community Multiscale Air Quality (CMAQ) model run with inputs and simulations generated by the EQUATES project. Pollutant concentrations are pulled from the model gridcell corresponding to Baltimore, Maryland, where the measurements for this study were taken. This dataset is associated with the following publication: Sapkota, S., P. Shekhar, B. Murphy, H. Pye, C. Hennigan, and M. El-Sayed. Seasonal Assessment of Secondary Organic Aerosol Formed through Aqueous Pathways in the Eastern United States. ACS Earth and Space Chemistry. American Chemical Society, Washington, DC, USA, 9(4): 876-887, (2025).