The sims zip file contains R code and accompanying files needed to run the R code. Overall this code demonstrates the R code used in the study is fully functional, documented, and reproducible and that this code could reproduce the simulation results from the study with sufficient computing time. The code as presented is for a single simulated dataset and will produce estimates and confidence intervals produced by all the methods used within the study when run on that one dataset. This dataset is associated with the following publication: Nethery, R., F. Mealli, J. Sacks, and F. Dominici. Evaluation of the Health Impacts of the 1990 Clean Air Act Amendments Using Causal Inference and Machine Learning. JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION. Taylor & Francis Group, London, UK, 1-12, (2020).