Dataset contains: sediment characterization (textural analysis, percent water content, percent organic content) from Susquehanna River sediments, radionuclide activities, and results from cesium sorption batch reactor experiments. This dataset is associated with the following publication: Ratliff, K., A. Mikelonis, and J. Duffy. Characterizing cesium sorption in freshwater settings using fluvial sediments and characteristic water chemistries. JOURNAL OF ENVIRONMENTAL MANAGEMENT. Elsevier Science Ltd, New York, NY, USA, 253: 7, (2020).