Total and methyl mercury, moisture content (%), and porosity were measured in Lake Michigan sediment by the U.S. Environmental Protection Agency/Office of Research and Development/National Health and Environmental Effects Research Laboratory/Mid-Continent Ecology Division/Large Lakes Research Station, Grosse Ile, MI. Both core and Ponar grab samples were collected. The samples were collected from 1994 through 1996. These mercury data were used in the LM2-Mercury model. This dataset is associated with the following publication: Zhang, X., K. Rygwelski , M. Rowe, R. Rossmann, and R. Kreis. Global and regional contributions to total mercury concentrations in Lake Michigan water. JOURNAL OF GREAT LAKES RESEARCH. International Association for Great Lakes Research, Ann Arbor, MI, USA, 42(1): 62-69, (2016).